A SYNERGISTIC TRIAD OF CHEMOTHERAPY, IMMUNE CHECKPOINT INHIBITORS, AND CALORIC RESTRICTION MIMETICS ERADICATES TUMORS IN MICE

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice

We have recently shown that chemotherapy with immunogenic cell death (ICD)-inducing agents can be Hockey advantageously combined with fasting regimens or caloric restriction mimetics (CRMs) to achieve superior tumor growth control via a T cell-dependent mechanism.Here, we show that the blockade of the CD11b-dependent extravasation of myeloid cells

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An Oxidation Gradient Straddling the Small Planet Radius Valley

We present a population-level view of volatile gas species (H _2 , He, H _2 O, O _2 , CO, CO _2 , CH _4 ) distribution during the sub-Neptune to rocky planet transition, revealing in detail the dynamic nature of small planet atmospheric compositions.Our novel model couples the atmospheric escape model IsoFATE with the magma ocean-atmosphere equilib

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Experimental Data and Simulations of Performance and Thermal Comfort in a Patient Room Equipped with Radiant Ceiling Panels

Hospitals require the highest energy demands in non-residential buildings.They provide healthcare 24/7/365 and, at the same time, they ensure indoor air quality, thermal comfort and sterility.However, several studies reveal that high indoor temperatures and low Women’s pajamas and workout loungewear relative humidity (RH) are often perceived in p

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